College Football Week 6 Predictions: Miami vs. Florida State Headlines the Slate.

Week 6 doesn’t hit quite as hard as last weekend’s chaos, but don’t be fooled this schedule has trap-game energy written all over it. Upsets thrive on weekends like this, when fans glance at the slate and think: “Nothing crazy will happen.” That’s usually when everything blows up.

The biggest spotlight? Miami vs. Florida State. The Hurricanes look like playoff contenders at No. 3, but Doak Campbell is where dreams go to die — especially when the Seminoles are underdogs with nothing to lose.

Let’s dive into the games that matter most.

Miami at Florida State (No. 3 vs. No. 19)

This one feels like it’s going to be a knife fight.

Miami has swagger right now. That offense is humming, the defense is mean, and they’re finally playing like a legit top-five team.

Florida State? They’ve been inconsistent, sure. But at home, in this rivalry, they get an extra gear. Their run game can bully defenses, and their defense has a knack for big turnovers.

Prediction: Miami survives, but barely. Rivalry games don’t care about rankings. I’ll take the Hurricanes by a late field goal.

Alabama vs. Vanderbilt (No. 11 vs. No. 17)

Alabama just smacked Georgia in Athens — vintage Nick Saban. But here comes Vanderbilt, the same team that stunned Bama last year. Don’t think Saban has forgotten. This feels like a full-on revenge tour stop.

Prediction: Alabama in a statement win.

Ohio State vs. Minnesota (No. 1 vs. unranked)

The Buckeyes are in “prove we’re No. 1” mode. Minnesota’s tough, but Ohio State is just deeper, faster, stronger — across the board.

Prediction: Ohio State cruises.

Texas Tech at Houston (No. 14 vs. unbeaten Houston)

This one is sneaky good. Texas Tech’s defense has been rock solid, but Houston has a quarterback who can light up a scoreboard in seconds. Big 12 shootout vibes.

Prediction: Houston edges Tech in a thriller.

Notre Dame vs. Boise State (No. 21 vs. last year’s playoff darling)

Notre Dame looks more balanced this year, but Boise has the kind of road-warrior defense that can steal one. Still, South Bend in October is a different animal.

Prediction: Notre Dame pulls away late.

Other Key Picks

Texas A&M over Mississippi State — Aggies too balanced.

Penn State over UCLA — but Bruins will make them sweat in L.A.

Texas over Florida — Longhorns keep marching.

Georgia over Kentucky — Bulldogs reassert dominance.

Michigan over Wisconsin — Wolverines grind it out.

BYU over West Virginia — home-field edge in Provo.

Summary

This week belongs to Miami–Florida State. Yes, Alabama and Ohio State will take care of business, but the Hurricanes heading into Tallahassee is the real test. If Miami leaves with a win, they cement themselves as a playoff lock.

But if Florida State pulls the upset? Say hello to another round of chaos in the CFP race.

I’m sticking with Miami — but I don’t feel great about it. Rivalry games never go as planned.