NFL Week 18 Odds: Point Spreads, Moneylines, Totals for Every Game

NFL Week 18 odds 2025: predictions: Picks, Spreads points, best Bet, lines, spreads for every game

We've reached the finish line of the 2025 regular season with Week 18 upon us. Some clubs will put a bow on the season before heading off into the offseason, while others will get their ducks in a row as they gear up for the playoffs. That creates a fascinating situation as it relates to the betting lines for these matchups. Because teams are in such different situations at this time of the year, the motivations for each organization are wildly different. 

NFL Week 18 Playoffs Schedule, Picks, Predictions, Odds: - Week 18 Previews - Week 18 Schedule Matchups -  Week 18 TV Schedule - Week 18 Odds -  Latest Playoffs Clinching Scenario - Playoffs Picture - Playoffs Bracket -   Week 18 Picks - 

 Dolphins v Patriots predictions - Chiefs v Raiders predictions - Lions v Bears predictions - Buccaneers v Panthers Predictions - Seahawks v 49ers predictions - NFL Games Today -  

Odds provided by BetMGM Sportsbook; 

Week 18 NFL Odds: Predictions, Picks, Spreads, Moneylines, and Totals for Every Game

Saturday, January 3

Carolina Panthers at Tampa Bay Buccaneers (4:30 p.m. ET, ABC/ESPN)

Spread: Buccaneers -3.5 (-110)

Moneyline: Buccaneers -185 | Panthers +154

Total: O/U 43.5

(Winner-take-all for NFC South title)

Seattle Seahawks at San Francisco 49ers (8:00 p.m. ET, ABC/ESPN)

Spread: 49ers -1 (-110) / Pick'em at some books

Moneyline: 49ers -110 | Seahawks -106

Total: O/U 44.5

(High-stakes game for NFC West and potential No. 1 seed)

Sunday, January 4

Green Bay Packers at Minnesota Vikings (1:00 p.m. ET, CBS)

Spread: Vikings -3 (-110)

Moneyline: Vikings -155 | Packers +130

Total: O/U 48.5

Cleveland Browns at Cincinnati Bengals (1:00 p.m. ET, CBS)

Spread: Bengals -7.5 (-110)

Moneyline: Bengals -350 | Browns +275

Total: O/U 45.5

Indianapolis Colts at Houston Texans (1:00 p.m. ET, CBS)

Spread: Texans -9.5 to -10 (-110)

Moneyline: Texans -450 | Colts +350

Total: O/U 46.5

Dallas Cowboys at New York Giants (1:00 p.m. ET, FOX)

Spread: Cowboys -3 (-110)

Moneyline: Cowboys -165 | Giants +140

Total: O/U 41.5

New Orleans Saints at Atlanta Falcons (1:00 p.m. ET, FOX)

Spread: Falcons -6 (-110)

Moneyline: Falcons -275 | Saints +225

Total: O/U 44.5

Tennessee Titans at Jacksonville Jaguars (1:00 p.m. ET, FOX)

Spread: Jaguars -11 (-110)

Moneyline: Jaguars -550 | Titans +400

Total: O/U 42.5

Los Angeles Chargers at Denver Broncos (4:25 p.m. ET, CBS)

Spread: Broncos -7.5 (-110)

Moneyline: Broncos -350 | Chargers +280

Total: O/U 38.5

Kansas City Chiefs at Las Vegas Raiders (4:25 p.m. ET, CBS)

Spread: Chiefs -6.5 (-110)

Moneyline: Chiefs -275 | Raiders +225

Total: O/U 40.5

Washington Commanders at Philadelphia Eagles (4:25 p.m. ET, CBS)

Spread: Eagles -7.5 (-110)

Moneyline: Eagles -350 | Commanders +280

Total: O/U 45.5

New York Jets at Buffalo Bills (4:25 p.m. ET, CBS)

Spread: Bills -12.5 to -13 (-110)

Moneyline: Bills -650 | Jets +450

Total: O/U 42.5

Miami Dolphins at New England Patriots (4:25 p.m. ET, FOX)

Spread: Dolphins -5 (-110)

Moneyline: Dolphins -225 | Patriots +185

Total: O/U 39.5

Arizona Cardinals at Los Angeles Rams (4:25 p.m. ET, FOX)

Spread: Rams -10 (-110)

Moneyline: Rams -450 | Cardinals +350

Total: O/U 47.5

Detroit Lions at Chicago Bears (4:25 p.m. ET, FOX)

Spread: Bears -2.5 (-110)

Moneyline: Bears -140 | Lions +120

Total: O/U 46.5

Baltimore Ravens at Pittsburgh Steelers (8:20 p.m. ET, NBC)

Spread: Ravens -3 (-110)

Moneyline: Ravens -165 | Steelers +140

Total: O/U 43.5

(Winner-take-all for AFC North title) 

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