10 Biggest March Madness Upsets of All-Time, Rankings: Biggest Underdog Upsets in NCAA Tournament History.
The NCAA tournament is coined March Madness because things don't go as planned.
Fairleigh Dickinson’s win over Purdue in the 2023 NCAA Tournament is the biggest upset in March Madness history.
As a 16-seed, the Knights were a 23-point underdog before shocking the Boilermakers, the second-ever 16-over-1 upset in tourney history.
Every season, underdogs turn into Cinderellas and the upsets don't stop until the final 40 minutes has run out. For a basketball fan, it is undeniably the best time of the year.
Below are the 10 craziest, most bracket-busting upsets the first weekend of the tournament has ever produced.
10 Biggest Men's March Madness Upsets of All-Time, Ranking
Year - Underdog - Favorite - Spread
2024 - TBD
2023 - (16) Fairleigh Dickinson (1) Purdue - 23
2012 - (15) Norfolk State (2) Missouri - +21
2018 - (16) UMBC (1) Virginia - +20.5
1997 - (15) Coppin State (2) South Carolina - +19
2022 - (15) Saint Peter's (2) Kentucky - +18
2001 - (15) Hampton (2) Iowa State - +17.5
2016 - (15) MTSU (2) Michigan State - +16.5
2021 - (15) Oral Roberts (2) Ohio State - +16.5
1999 - (15) Weber State (2) North Carolina - +15
2023 - (15) Princeton (2) Arizona - +15
2010 - (14) Ohio (2) Georgetown - +14
2015 - (14) UAB (3) Iowa State - +14
2005 - (14) Bucknell (3) Kansas - +13
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