NFL wild-card playoff picks 2022: Predictions for wild-card games: 49ers upset Cowboys; Bills, Cardinals wins, Odds, Spreads, bet lines.

The NFL Super Wild Card Weekend 2022 will feature five games that are rematches from the regular season. The only one that isn't is Cowboys vs. 49ers, and these two storied franchises will meet in the NFL playoff bracket for the first time since three straight matchups during the 1992-94 seasons.

Dallas is a three-point favorite at Caesars Sportsbook in the latest Wild Card Weekend NFL odds, with the over-under set at 50.5.

With Week 18 in the books, that means it's now time for the postseason, and up first, we have the playoff round that I love to hate: The wild-card round.

Now, it's a mad dash to SoFi Stadium for Super Bowl LVI in Los Angeles, beginning with Super Wild Card Weekend.

NFL odds, lines, bracket, picks, spreads, predictions for Wild Card Weekend games for 2022 schedule:

Super Wild Card Weekend Picks, Odds, Bet lines, Spreads --- Powered by Caesars Sportsbook

No. 5 Las Vegas Raiders (10-7) at No. 4 Cincinnati Bengals (10-7)

Saturday, 4:30 p.m. ET (NBC)

Latest Odds: Cincinnati Bengals -5.5

Opening line: Bengals -6.5

Spreads: Raiders at Bengals ( 48.5)

The pick: Bengals 30-23 over Raiders

Record picking Raiders games this season: 8-9 straight-up, 10-7 against the spread

Record picking Bengals games this season: 12-5 straight-up, 8-7-2 against the spread

No. 6 New England Patriots (10-7) at No. 3 Buffalo Billa (11-6)

Saturday, 8:15 p.m. ET (CBS)

Latest Odds: Buffalo Bills -4

Opening line: Bills -4.5

Spreads: Patriots at Bills ( 44)

The pick: Bills 24-17 over Patriots

Record picking Patriots games this season: 12-5 straight-up, 11-6 against the spread

Record picking Bills games this season: 11-6 straight-up, 9-8 against the spread

No. 7 Philadelphia Eagles (9-8) at No. 2 Tampa Bay Buccaneers (13-4)

Sunday, 1 p.m. ET (Fox)

Latest Odds: Tampa Bay Buccaneers -8.5

Opening line: Buccaneers -9

Spreads: Eagles at Buccaneers (46)

The pick: Buccaneers 27-20 over Eagles

Record picking Eagles games this season: 11-6 straight-up, 7-10 against the spread

Record picking Buccaneers games this season: 12-5 straight-up, 6-11 against the spread

No. 6 San Francisco 49ers (10-7) at No. 3 Dallas Cowboys (12-5)

Sunday, 4:30 p.m. ET (CBS/Nickelodeon)

Latest Odds: Dallas Cowboys -3

Opening line: Cowboys -3

Spreads: 49ers at Cowboys (51)

The pick: 49ers 27-24 over Cowboys

Record picking 49ers games this season: 11-6 straight-up, 9-8 against the spread

Record picking Cowboys games this season: 11-6 straight-up, 9-8 against the spread

No. 7 Pittsburgh Steelers (9-7-1) at No. 2 Kansas City Chiefs (12-5)

Sunday, 8:15 p.m. ET (NBC)

Latest Odds:Kansas City Chiefs -12.5

Opening line: Chiefs -12.5

Spreads: Steelers at Chiefs ( 46.5)

The pick: Chiefs 30-20 over Steelers

Record picking Steelers games this season: 12-4-1 straight-up, 9-8 against the spread

Record picking Chiefs games this season: 12-5 straight-up, 11-6 against the spread

No. 5 Arizona Cardinals (11-6) at No. 4 Los Angeles Rams (12-5)

Monday, 8:15 p.m. ET (ABC/ESPN)

Latest Odds:Los Angeles Rams -4

Opening line: Rams -4.5

Spreads: Cardinals at Rams (50.0)

The pick: Rams 34-31 over Cardinals

Record picking Cardinals games this season: 6-11 straight-up, 5-12 against the spread

Record picking Rams games this season: 12-5 straight-up, 9-8 against the spread

_________

Source __ CBSSports.com