NFL Week 13 Odds: Betting Lines, Point Spreads, Over/Under Totals

NFL Week 13 Odds: Point Spreads, Moneylines, and Totals for Every Game, best bets, lines

It's time to get ready for the best week of the NFL regular season. BYE weeks are on a break as all 32 NFL teams will strap on their helmets for Thanksgiving week.

Week 13 of the 2025 NFL regular season is on the immediate horizon and it’s a feast – quite literally – for football fans. It begins with a traditional Thanksgiving trio of games on Thursday, with the Lions, and Packers looking to treat their home crowds to victories. There is also a Black Friday game on offer, as Bears host Eagles in an AFC showdown. The week also features Broncos vs Commanders on SNF and wraps up with the Giants visiting New England on MNF.  

Six teams are on bye this week in the NFL, and just two teams will sit out next week, so byes are winding down, and the playoff race is heating up.

Here are the NFL betting odds for each game in Week 13. (Via BetMgM)

THURSDAY, NOV. 27

PACKERS @ LIONS 

Spread: Lions -2.5

Moneyline: Lions -142, Packers +120

O/U: 48.5

CHIEFS @ COWBOYS

Spread: Chiefs -3.5

Moneyline: Chiefs -170, Cowboys +142

O/U: 52.5

BENGALS @ RAVENS

Spread: Ravens -7

Moneyline: Ravens -340, Bengals +270

O/U: 51.5

FRIDAY, NOV. 28

BEARS @ EAGLES

Spread: Eagles -7

Moneyline: Eagles -325, Bears +260

O/U: 44.5

SUNDAY, NOV. 30

TEXANS @ COLTS

Spread: Colts -4.5

Moneyline: Colts -225, Texans +185

O/U: 44.5

49ERS @ BROWNS

Spread: 49ers -6

Moneyline: 49ers -298, Browns +240

O/U: 39.5

SAINTS @ DOLPHINS

Spread: Dolphins -6

Moneyline: Dolphins -250, Saints +205

O/U: 41.5

JAGUARS @ TITANS

Spread: Jaguars -6.5

Moneyline: Jaguars -325, Titans +260

O/U: 42.5

FALCONS @ JETS

Spread: Falcons -2.5

Moneyline: Falcons -142, Jets +120

O/U: 39.5

RAMS @ PANTHERS

Spread: Rams -10.5

Moneyline: Rams -600, Panthers +440

O/U: 45.5

CARDINALS @ BUCCANEERS

Spread: Buccaneers -3

Moneyline: Buccaneers -155, Cardinals +130

O/U: 44.5

VIKINGS @ SEAHAWKS

Spread: Seahawks -10.5

Moneyline: Seahawks -500, Vikings +380

O/U: 41.5

RAIDERS @ CHARGERS

Spread: Chargers -10

Moneyline: Chargers -625, Raiders +455

O/U: 41.5

BILLS @ STEELERS

Spread: Bills -3.5

Moneyline: Bills -198, Steelers +164

O/U: 47.5

BRONCOS @ COMMANDERS

Spread: Broncos -6.5

Moneyline: Broncos -310, Commanders +250

O/U: 43.5

MONDAY, DEC. 1

GIANTS @ PATRIOTS

Spread: Patriots -7.5

Moneyline: Patriots -425, Giants +330

O/U: 46.5  

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