2026 NFL Week 5 Odds, betting Lines: Point Spreads, Moneylines & Totals for Week 5 games.
The Cowboys opened as sizable favorites and remain the biggest favorite of the week.The Cincinnati Bengals rank as the second-biggest favorite, visiting the Miami Dolphins as road favorites. Several games feature spreads of four points or fewer.
The Detroit Lions-Arizona Cardinals and Buffalo Bills-Los Angeles Rams matchups carry the highest totals of the week.The Kansas City Chiefs and Carolina Panthers are on bye this week.
Odds are courtesy of major sportsbooks (including DraftKings) and are subject to change.
NFL Week 5 Odds Today: Betting Lines, Spread for Sunday Games
THURSDAY, OCT. 8
Tampa Bay Buccaneers @ Dallas Cowboys
Point Spread: Cowboys -9.5
Moneyline: Cowboys -500, Buccaneers +380
Total Over/Under: 48.5
SUNDAY, OCT. 11
Philadelphia Eagles @ Jacksonville Jaguars
Point Spread: Jaguars -7.5
Moneyline: Jaguars -300, Eagles +240
Total Over/Under: 41.5
Chicago Bears @ Green Bay Packers
Point Spread: Bears -2.5
Moneyline: Bears -142, Packers +120
Total Over/Under: 45.5
Cincinnati Bengals @ Miami Dolphins
Point Spread: Bengals -6.5
Moneyline: Bengals -325, Dolphins +260
Total Over/Under: 42.5
Indianapolis Colts @ Pittsburgh Steelers
Point Spread: Steelers -2.5
Moneyline: Steelers -145, Colts +122
Total Over/Under: 44.5
New York Giants @ Washington Commanders
Point Spread: Commanders -3.5
Moneyline: Commanders -180, Giants +155
Total Over/Under: 41.5
Cleveland Browns @ New York Jets
Point Spread: Jets -2
Moneyline: Jets -135, Browns +115
Total Over/Under: 39.5
Las Vegas Raiders @ New England Patriots
Point Spread: Patriots -3.5
Moneyline: Patriots -190, Raiders +160
Total Over/Under: 45
Houston Texans @ Tennessee Titans
Point Spread: Texans -7.5
Moneyline: Texans -350, Titans +280
Total Over/Under: 38
Minnesota Vikings @ New Orleans Saints
Point Spread: Vikings -2.5
Moneyline: Vikings -140, Saints +120
Total Over/Under: 41.5
Denver Broncos @ Los Angeles Chargers
Point Spread: Broncos -3.5
Moneyline: Broncos -180, Chargers +155
Total Over/Under: 41.5
San Francisco 49ers @ Seattle Seahawks
Point Spread: Seahawks -3
Moneyline: Seahawks -155, 49ers +135
Total Over/Under: 46
Detroit Lions @ Arizona Cardinals
Point Spread: Lions -5.5
Moneyline: Lions -250, Cardinals +205
Total Over/Under: 54.5
Baltimore Ravens @ Atlanta Falcons
Point Spread: Falcons -3
Moneyline: Falcons -155, Ravens +135
Total Over/Under: 43.5
MONDAY, OCT. 12
Buffalo Bills @ Los Angeles Rams
Point Spread: Rams -3
Moneyline: Rams -155, Bills +135
Total Over/Under: 54.5
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