NFL Week 3 Betting Odds, Lines, Spreads, Totals, Bets, UPDATED

2025 NFL Schedule: Full Week 3 best Odds: Spreads, Totals & Moneylines for Every Game.

Week 3 gets underway with a matchup of AFC East rivals when the Miami Dolphins visit the Buffalo Bills on "Thursday Night Football."

The Bills cruised past the New York Jets in Week 2 to move to 2-0, while the Dolphins dropped to 0-2 after falling to the Patriots in New England.

Not surprisingly, the Bills are the biggest favorite (-13.5) on the Week 3 slate.

Sunday afternoon features two matchups of undefeated teams, with the Philadelphia Eagles (-3.5) hosting the Los Angeles Rams and the Arizona Cardinals hitting the road to face the San Francisco 49ers (-1.5).

"Sunday Night Football" will feature a pair of winless teams: the New York Giants and... the Kansas City Chiefs. The Giants fell to 0-2 after a wild finish in Dallas, and the Chiefs remained winless after a loss to the Eagles in their Super Bowl rematch.

Sportshistori.com have broke down the numbers immediately after every NFL Week 3 game, including scores, winners results, Top Fantasy Stars & performances and more.

2025 NFL scores: Week 3, Odds, moneyline, spread, U/O, totals for every game.

Miami Dolphins vs. Buffalo Bills -12.5

Thursday, 8:15 p.m., Prime Video

Line movement: Opened Bills -10.5

Money Line: Dolphins (+550); Bills (-900)

Total: 49.5; Opened: 48.5

FPI favorite: Bills by 10.8 with a 76.6% probability to win the game outright

New York Jets vs. Tampa Bay Buccaneers -6.5

Sunday, 1 p.m., FOX

Money Line: Jets (+230); Buccaneers (-280)

Total: 44.5; Opened: 44.5

FPI favorite: Buccaneers by 8.4 with a 69.97% probability to win the game outright

Indianapolis Colts -3.5 vs. Tennessee Titans

Sunday, 1 p.m., CBS

Money Line: Colts (-195); Titans (+165)

Total: 43.5; Opened: 43.5

FPI favorite: Colts by 6.1 with a 66.13% probability to win the game outright

Las Vegas Raiders vs. Washington Commanders -3.5

Sunday, 1 p.m., FOX

Line movement: Opened Commanders -6.5

Money Line: Raiders (+155); Commanders (-185)

Total: 43.5; Opened: 47.5

FPI favorite: Commanders by 4.5 with a 61.37% probability to win the game
outright

Los Angeles Rams vs. Philadelphia Eagles -3.5

Sunday, 1 p.m., FOX

Money Line: Rams (+160); Eagles (-190)

Total: 44.5; Opened: 45.5

FPI favorite: Eagles by 2.9 with a 57.73% probability to win the game outright

Atlanta Falcons -5.5 vs. Carolina Panthers

Sunday, 1 p.m., FOX

Line movement: Opened Falcons -3.5

Money Line: Falcons (-270); Panthers (+220)

Total: 43.5; Opened: 44.5

FPI favorite: Falcons by 2.7 with a 57.07% probability to win the game outright

Houston Texans vs. Jacksonville Jaguars -1.5

Sunday, 1 p.m., CBS

Money Line: Texans (+105); Jaguars (-125)

Total: 43.5; Opened: 43.5

FPI favorite: Jaguars by 1.3 with a 52.6% probability to win the game outright

Green Bay Packers -7.5 vs. Cleveland Browns

Sunday, 1 p.m., FOX

Money Line: Packers (-450); Browns (+340)

Total: 41.5; Opened: 43.5

FPI favorite: Packers by 8.3 with a 70.2% probability to win the game outright

Pittsburgh Steelers -1.5 vs. New England Patriots

Sunday, 1 p.m., CBS

Money Line: Steelers (-130); Patriots (+110)

Total: 44.5; Opened: 44.5

FPI favorite: Patriots by 0 with a 48.4% probability to win the game outright

Cincinnati Bengals vs. Minnesota Vikings -3.5

Sunday, 1 p.m., CBS

Line movement: Opened Vikings -5.5

Money Line: Bengals (+130); Vikings (-150)

Total: 41.5; Opened: 44.5

FPI favorite: Vikings by 2.1 with a 56.8% probability to win the game outright

Denver Broncos vs. Los Angeles Chargers -2.5

Sunday, 4:05 p.m., CBS

Money Line: Broncos (+125); Chargers (-145)

Total: 45.5; Opened: 46.5

FPI favorite: Chargers by 2.5 with a 55.87% probability to win the game outright

New Orleans Saints vs. Seattle Seahawks -7.5

Sunday, 4:05 p.m., CBS

Money Line: Saints (+300); Seahawks (-400)

Total: 41.5; Opened: 42.5

FPI favorite: Seahawks by 5.7 with a 65% probability to win the game outright

Arizona Cardinals vs. San Francisco 49ers -1.5

Sunday, 4:25 p.m., FOX

Line movement: Opened Cardinals -1.5

Money Line: Cardinals (+105); 49ers (-125)

Total: 44.5; Opened: 43.5

FPI favorite: Cardinals by 0.9 with a 51.47% probability to win the game outright

Dallas Cowboys -1.5 vs. Chicago Bears

Sunday, 4:25 p.m., FOX

Line movement: Opened Bears -1.5

Money Line: Cowboys (-115); Bears (-105)

Total: 49.5; Opened: 49.5

FPI favorite: Cowboys by 1.4 with a 54.4% probability to win the game outright

Kansas City Chiefs -6.5 vs. New York Giants

Sunday, 8:20 p.m., NBC

Money Line: Chiefs (-290); Giants (+240)

Total: 45.5; Opened: 42.5

FPI favorite: Chiefs by 6.6 with a 66.47% probability to win the game outright

Detroit Lions vs. Baltimore Ravens -4.5

Monday, 8:15 p.m., ABC, ESPN

Money Line: Lions (+200); Ravens (-240)

Total: 52.5; Opened: 52.5

FPI favorite: Ravens by 2.6 with a 57.4% probability to win the game outright

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